Having installed Update Rollup 9 for Exchange 2007 on a number of different sites we finally had one that broke Outlook Web Access. OWA would load yet several images were just placeholders and after logging in no actual inbox could be read as all the Fonts and styling were screwed up.
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In our case running the UpdateOWA.ps1 resolved the issue.
Step 2) Navigate to your Exchange Bin directory via the management shell – usually C:\Program Files\Microsoft\Exchange Server\Bin
Step 3) Run the UpdateOWA.ps1 script (done by entering .\UpdateOWA.ps1)